The Pharma Indexhttps://thepharmaindex.comA magazine about molecules, medicine and the people behind them.The Nobel Prize Celebrates Breakthroughs. Who Celebrates the Foundations?https://thepharmaindex.com/story/who-celebrates-the-foundations/https://thepharmaindex.com/story/who-celebrates-the-foundations/Mon, 09 Nov 2026 00:00:00 +0000From a 1964 bacterial genetics experiment to AlphaFold, the genealogy of protein modeling is longer and more crowded than any citation can hold.A Protein That Switches Folds. Why Should We Care?https://thepharmaindex.com/story/a-protein-that-switches-folds/https://thepharmaindex.com/story/a-protein-that-switches-folds/Sun, 08 Nov 2026 00:00:00 +0000Because our best prediction tools were trained to give one answer.The Protein That Refuses to Have One Shapehttps://thepharmaindex.com/story/the-protein-that-refuses-to-have-one-shape/https://thepharmaindex.com/story/the-protein-that-refuses-to-have-one-shape/Sat, 07 Nov 2026 00:00:00 +0000Textbooks promised one sequence, one structure. Lymphotactin never read them.America Has a Peptide Obsessionhttps://thepharmaindex.com/story/america-has-a-peptide-obsession/https://thepharmaindex.com/story/america-has-a-peptide-obsession/Thu, 05 Nov 2026 00:00:00 +0000A word that once lived in biochemistry textbooks now sells serums, injections and an entire theory of self-improvement.The 1964 Experiment Where Two Wrongs Made a Righthttps://thepharmaindex.com/story/two-wrongs-made-a-right/https://thepharmaindex.com/story/two-wrongs-made-a-right/Wed, 04 Nov 2026 00:00:00 +0000A broken enzyme, a second mutation and an early hint of how residues talk to each other.Charles Yanofsky and the Biology Behind the Breakthroughhttps://thepharmaindex.com/story/charles-yanofsky-and-the-biology-behind-the-breakthrough/https://thepharmaindex.com/story/charles-yanofsky-and-the-biology-behind-the-breakthrough/Mon, 02 Nov 2026 00:00:00 +0000He showed that genes and proteins line up, then spent decades working out how a cell reads the fine print.The Signalhttps://thepharmaindex.com/story/the-signal-coming-soon/https://thepharmaindex.com/story/the-signal-coming-soon/Sun, 01 Nov 2026 00:00:00 +0000Our presenter-led broadcast on molecules, medicine and the people behind them. The first episode is in production.Anfinsen's Ribonuclease Is Still the Best Demo in Biochemistryhttps://thepharmaindex.com/story/anfinsens-ribonuclease/https://thepharmaindex.com/story/anfinsens-ribonuclease/Sat, 31 Oct 2026 00:00:00 +0000Unfold an enzyme, take away the denaturant and watch it remember what it was.Does the Nobel Prize Understand Modern Science?https://thepharmaindex.com/story/does-the-nobel-prize-understand-modern-science/https://thepharmaindex.com/story/does-the-nobel-prize-understand-modern-science/Thu, 29 Oct 2026 00:00:00 +0000The rules suit a handful of names at a lab bench. Today's discoveries come with author lists and server bills.Can We Design a Protein That Has Never Existed?https://thepharmaindex.com/story/can-we-design-a-protein-that-has-never-existed/https://thepharmaindex.com/story/can-we-design-a-protein-that-has-never-existed/Sat, 24 Oct 2026 00:00:00 +0000We already have. The harder question is whether we can make new ones that do useful work.How Two Scientists Took an Antibody Aparthttps://thepharmaindex.com/story/the-shape-of-an-antibody/https://thepharmaindex.com/story/the-shape-of-an-antibody/Tue, 20 Oct 2026 00:00:00 +0000One used an enzyme, the other used chemistry. Together they found the molecule behind a whole class of drugs.